Ap Bio Molecular Genetics Essay

Ap Bio Molecular Genetics Essay-26
The ribosome facilitates decoding by inducing the binding of complementary t RNA anticodon sequences to m RNA codons.The t RNAs carry specific amino acids that are chained together into a polypeptide as the m RNA passes through and is read by the ribosome.The ribosome is a multi-subunit structure containing r RNA and proteins.

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In eukaryotes, translation occurs in the cytosol or across the membrane of the endoplasmic reticulum in a process called co-translational translocation.The successive amino acids added to the chain are matched to successive nucleotide triplets in the m RNA.In this way, the sequence of nucleotides in the template m RNA chain determines the sequence of amino acids in the generated polypeptide.In molecular biology and genetics, translation is the process in which ribosomes in the cytoplasm or ER synthesize proteins after the process of transcription of DNA to RNA in the cell's nucleus. In translation, messenger RNA (m RNA) is decoded in the ribosome decoding center to produce a specific amino acid chain, or polypeptide.The polypeptide later folds into an active protein and performs its functions in the cell.Prokaryotic ribosomes have a different structure from that of eukaryotic ribosomes, and thus antibiotics can specifically target bacterial infections without any harm to a eukaryotic host's cells.The basic process of translation is the addition of one amino acid at a time to the end of the polypeptide being formed. A ribosome is made up of two subunits, a small 40S subunit and a large 60S subunit.A number of antibiotics act by inhibiting translation.These include clindamycin, anisomycin, cycloheximide, chloramphenicol, tetracycline, streptomycin, erythromycin, and puromycin.Translation proceeds in three phases: The three phases of translation initiation polymerase binds to the DNA strand and moves along until the small ribosomal subunit binds to the DNA.Elongation is initiated when the large subunit attaches and termination ends the process of elongation.


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